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SCO

Linked experiment: EXP001833

Linked peptide: Bi-specific D1 (one PMO on each Pip6a terminus)

Linked paper: Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy (2015)

RNA overview

RNA Type

SCO

Payload/target

Dual splice-switching: Dmd exon23 + Acvr2b exon5 (two PMOs on one Pip6a)

Target gene/transcript

not reported

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:GGCCAAACCTCGGCTTACCTGAAATa

Sense strand

GGCCAAACCTCGGCTTACCTGAAATa

Antisense strand

Chemical modifications

RNA modifications

not reported