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ASO

Linked experiment: EXP001844

Linked peptide: OK-102 (stearoyl-oligopeptide)

Linked paper: Functional peptide nanocarriers for delivery of novel anti-RelA RNA interference agents as a topical treatment of atopic dermatitis (2015)

RNA overview

RNA Type

ASO

Payload/target

RelA (NF-κB p65) mRNA

Target gene/transcript

not reported

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:AUACUAUUCGACACGCGGAAGUUCC; antisense:CUUAUGAUAAGCUGUGCGCUUCAAGG

Sense strand

AUACUAUUCGACACGCGGAAGUUCC

Antisense strand

CUUAUGAUAAGCUGUGCGCUUCAAGG

Chemical modifications

RNA modifications

anti-RelA PnkRNA1 (51-mer); sequences/structures provided in paper Fig.1 but not machine-extracted from PDF text. Novel RNAi agent (PnkRNA1) incorporating a proline-derived molecule; sequence shown in Fig.1 (not fully captured in parsed text).