siRNA

Linked experiment: EXP001852

Linked peptide: Cholesterol-DP7-PEG2-T7 peptide

Linked paper: A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery system targeting gliomas for brain tumor immunotherapy (2024)

RNA overview

RNA Type: siRNA
Payload/target: Biodistribution/BBB penetration screening (fluorescent siRNA; no therapeutic target readout)
Target gene/transcript: fluorescent

Sequence information

Sequence reported in source article: no
RNA sequence: not reported
Sense strand
Antisense strand

Chemical modifications

RNA modifications: Cy5-siRNA; administered i.v. and imaged ex vivo (IVIS) and by brain section CLSM at 4 h.