ASO

Linked experiment: EXP001866

Linked peptide: pVEC

Linked paper: Targeting glmS Ribozyme with Chimeric Antisense Oligonucleotides for Antibacterial Drug Development (2021)

RNA overview

RNA Type: ASO
Payload/target: Combination: ASO1 targets glmS riboswitch; ASO2 targets nagA mRNA (S. aureus)
Target gene/transcript: nagA

Sequence information

Sequence reported in source article: yes
RNA sequence: ASO1 with all applied modifications is 5′C1T1T1T2A2A2C2T2G2T2A2C2T2G1C1C2
Sense strand
Antisense strand

Chemical modifications

RNA modifications: phosphorothioate (PS) + 2′-O-alkyl (2′-O-CH3) mix of 1st/2nd generation modifications