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siRNA

Linked experiment: EXP001895

Linked peptide: Grb2 (SH2 domain)

Linked paper: Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Docking Study (2017)

RNA overview

RNA Type

siRNA

Payload/target

GAPDH siRNA; HPV16 E6 siRNA (computational models)

Target gene/transcript

GAPDH

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:GACGUAAACGGCCACAAGUUC; GCAACAGUUACUGCGACGUUU; antisense:ACUUGUGGCCGUUUACGUCGC; ACGUCGCAGUAACUGUUGCUU

Sense strand

GACGUAAACGGCCACAAGUUC; GCAACAGUUACUGCGACGUUU

Antisense strand

ACUUGUGGCCGUUUACGUCGC; ACGUCGCAGUAACUGUUGCUU

Chemical modifications

RNA modifications

Idealized A-form and B-form siRNA (modeled)