siRNA

Linked experiment: EXP001921

Linked peptide: Tat-LK15

Linked paper: Targeting neuronal nitric oxide synthase by a cell penetrating peptide Tat-LK15/siRNA bioconjugate (2017)

RNA overview

RNA Type: siRNA
Payload/target: nNOS (neuronal nitric oxide synthase) siRNA-3; Sense 5'-CAAGUUCCGCCUCACGUAUdTdT-3', Antisense 5'-AUACGUGAGGCGGAACUUGdTdT-3'
Target gene/transcript: sense

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:CAAGUUCCGCCUCACGUAUdTdT; antisense:AUACGUGAGGCGGAACUUGdTdT
Sense strand: CAAGUUCCGCCUCACGUAUdTdT
Antisense strand: AUACGUGAGGCGGAACUUGdTdT

Chemical modifications

RNA modifications: 3' dTdT overhangs; FAM-labeled siRNA used for uptake assays