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SCO

Linked experiment: EXP002143

Linked peptide: (R-Ahx-R)4

Linked paper: Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents (2006)

RNA overview

RNA Type

SCO

Payload/target

PMO705 steric-blocking morpholino targeting aberrant splice site in human β-globin intron 2 within HeLa pLuc705 luciferase splice-correction reporter

Target gene/transcript

luciferase; aberrant splice site in human β-globin intron 2

Sequence information

Sequence reported in source article

no

RNA sequence

not reported

Sense strand

Antisense strand

Chemical modifications

RNA modifications

PMO; some 3′-fluorescein (FAM) labeled PMO for uptake assays; peptide conjugated to 5′-piperazine-functionalized PMO