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miRNA

Linked experiment: EXP002183

Linked peptide: TATp

Linked paper: Mixed Nanosized Polymeric Micelles as Promoter of Doxorubicin and miRNA-34a Co-Delivery Triggered by Dual Stimuli in Tumor Tissue (2016)

RNA overview

RNA Type

miRNA

Payload/target

miRNA-34a (Bcl2, survivin, notch1)

Target gene/transcript

PLK1

Sequence information

Sequence reported in source article

yes

RNA sequence

survivin forward: 5′-AGAACTGGCCCTTCTTGGAGG-3′ survivin reverse: 5′-CTTTTTATGTTCCTCTATGGGGTC-3′ Bcl2 forward: 5′-CCTTGTGGATGACTGAGTACC-3′ Blc2 reverse: 5′AGCCAGGAGAAATCAAACAGAG-3′ notch1 forward: 5′GACAGCCTCAACGGGTACAA-3′ notch1 reverse: 5′-ATACACGTGCCCTGGTTCAG-3′ β-actin forward: 5′-CTCTTCCAGCCTTCCTTCCT-3′β-actin reverse: 5′AGCACTGTGTTGGCGTACAG-3′

Sense strand

Antisense strand

Chemical modifications

RNA modifications

S-S-PE lipid conjugation (GSH-cleavable); FAM/fluorescein