siRNA

Linked experiment: EXP002440

Linked peptide: ApoB11-9R

Linked paper: Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease (2019)

RNA overview

RNA Type: siRNA
Payload/target: siα-syn
Target gene/transcript: α-synuclein / SNCA

Sequence information

Sequence reported in source article: yes
RNA sequence: GAC UUU CAA AGG CCA AGG A
Sense strand: GACUUUCAAAGGCCAAGGA
Antisense strand

Chemical modifications

RNA modifications: FITC-labeled siRNA used for biodistribution/uptake; unlabeled siRNA used for repeated treatment