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siRNA

Linked experiment: EXP002451

Linked peptide: Tat48–60 / sihsp90α complex + 17-AAG

Linked paper: Can RNAi-mediated hsp90α knockdown in combination with 17-AAG be a therapy for glioma? (2013)

RNA overview

RNA Type
siRNA
Payload/target
sihsp90α / siHsp90AA1
Target gene/transcript
Hsp90AA1 / Hsp90α

Sequence information

Sequence reported in source article
yes
RNA sequence
sense: 5′-CGUGAUAAAGAAGUAAGCGtt-3′; antisense: 5′-CGCUUACUUCUUUAUCACGtt-3′
Sense strand
CGUGAUAAAGAAGUAAGCGtt
Antisense strand
CGCUUACUUCUUUAUCACGtt

Chemical modifications

RNA modifications
lowercase tt overhangs reported; siRNA complexed non-covalently with Tat48–60 CPP