ASO

Linked experiment: EXP002500

Linked peptide: (KFF)3K-L bacterial penetration peptide

Linked paper: A Novel Peptide Nucleic Acid against the Cytidine Monophosphate Kinase of S. aureus Inhibits Staphylococcal Infection In Vivo (2019)

RNA overview

RNA Type: ASO
Payload/target: ASP-pyrH1
Target gene/transcript: pyrH mRNA / uridylate kinase

Sequence information

Sequence reported in source article: yes
RNA sequence: CCATTTTCTT
Sense strand
Antisense strand: CCATTTTCTT

Chemical modifications

RNA modifications: Peptide nucleic acid (PNA) backbone; antisense sequence targeting translation initiation region; conjugated to (KFF)3K-L peptide