Back to browse

PNA (splice-switching antisense)

Linked experiment: EXP000843

Linked peptide: Tat

Linked paper: Induction of splice correction by cell-penetrating peptide nucleic acids (2006)

RNA fields

RNA Type

PNA (splice-switching antisense)

RNA Payload Or Target

β-globin intron 2 aberrant splice site in luciferase reporter (HeLa pLuc 705) (M705 splice-correcting PNA)

RNA Modifications

PNA M705: CysKKCCTCTTACCTCAGTTACAKK-NH2; inverted control (4 bases inverted). Some conjugates fluorescein-labeled on C-terminal Lys for uptake assays.