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PNA (peptide nucleic acid)

Linked experiment: EXP000887

Linked peptide: Penetratin

Linked paper: Structural Requirements for Cellular Uptake and Antisense Activity of Peptide Nucleic Acids Conjugated with Various Peptides (2006)

RNA fields

RNA Type

PNA (peptide nucleic acid)

RNA Payload Or Target

18-mer PNA targeting IVS2-705 cryptic splice site in β-globin intron 2 inserted into luciferase reporter (splice correction)

RNA Modifications

PNA with (AEEA/ethylene glycol) spacers (ooo) x3 at both termini; some conjugates FAM-labeled for confocal microscopy