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ASO

Linked experiment: EXP001149

Linked peptide: ETWWK

Linked paper: Advancing Antisense Oligonucleotide Delivery through Click Chemistry Based Chemical Conjugation with Designed Short Non-Cationic Peptides for Duchenne Muscular Dystrophy (2025)

RNA fields

RNA Type

ASO

RNA Payload Or Target

DMD dystrophin exon 51 skipping (restore dystrophin protein)

RNA Modifications

2'-O-methyl phosphorothioate (2'-OMePS) ASO; 5' MMT-Amino C-6 CED phosphoramidite linker then alkyne linker for CuAAC; FAM label used in uptake assays