Back to browse

ASO (antisense oligonucleotide; steric-blocking)

Linked experiment: EXP001727

Linked peptide: R9 (nona-arginine)

Linked paper: The nuclear concentration required for antisense oligonucleotide activity in myotonic dystrophy cells (2019)

RNA fields

RNA Type

ASO (antisense oligonucleotide; steric-blocking)

RNA Payload Or Target

CAG5 (triplet repeat-targeting ASO; sequence mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG)

RNA Modifications

Fully 2'-O-methyl (m) + phosphorothioate (*) 15-mer; Cy5 label at 5' used for imaging/quantitation in some experiments