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siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)

Linked experiment: EXP001980

Linked peptide: Ab-CPP-LSP-siRNA-Cy3 (ARC; cetuximab–PEG–LMWP–AANL–siRNA)

Linked paper: Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzyme cleavable linker mediated effective intracellular delivery of siRNA (2021)

RNA fields

RNA Type

siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)

RNA Payload Or Target

EGFP knockdown in xenograft tumors (in vivo gene silencing)

RNA Modifications

Cy3-labeled anti-EGFP siRNA used for tumor section imaging + quantification; anti-EGFP siRNA for silencing.