|
EXP001867
|
Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells
|
2015 |
Proteinticle(ECP+CAP+CPP+VRP)
|
siRNA (poly-siRNA)
|
yes |
no |
yes |
no |
no |
|
EXP001868
|
Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells
|
2015 |
Proteinticle(ECP+CAP+VRP) (CPP-free)
|
siRNA (poly-siRNA)
|
yes |
no |
|
no |
no |
|
EXP001869
|
Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells
|
2015 |
Proteinticle(ECP+CAP+CPP) (CTP-free)
|
siRNA (poly-siRNA)
|
yes |
no |
|
no |
no |
|
EXP001870
|
Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells
|
2015 |
Proteinticle(ECP+CAP+CPP+ERP)
|
siRNA (poly-siRNA)
|
yes |
no |
yes |
no |
no |
|
EXP001871
|
Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells
|
2015 |
Proteinticle(ECP+CAP+ERP) (CPP-free)
|
siRNA (poly-siRNA)
|
yes |
no |
|
no |
no |
|
EXP001872
|
Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells
|
2015 |
Proteinticle(ECP+CAP+CPP) (CTP-free)
|
siRNA (poly-siRNA)
|
yes |
no |
|
no |
no |
|
EXP001873
|
Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells
|
2015 |
Proteinticle(ECP+CAP+CPP+VRP)
|
siRNA (poly-siRNA)
|
yes |
yes |
yes |
no |
no |
|
EXP001874
|
Engineered Proteinticles for Targeted Delivery of siRNA to Cancer Cells
|
2015 |
Proteinticle(ECP+CAP+CPP+VRP) + scrambled siRNA
|
siRNA (poly-siRNA)
|
yes |
no |
yes |
no |
no |
|
EXP001875
|
iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to P…
|
2018 |
iRGD TPN (PEGylated) [pTP-iRGD + pTP-PEG-iRGD]
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP001876
|
iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to P…
|
2018 |
iRGD TPN (PEGylated) [15:2.5:1 pTP-TAM-iRGD:pTP-PEG(5k)-iRGD:siRNA]
|
siRNA
|
yes |
|
|
yes |
yes |
|
EXP001877
|
iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to P…
|
2018 |
iRGD TPN (PEGylated) therapeutic dosing [15:2.5:1 pTP-TAM-iRGD:pTP-PEG(5k)-iRGD:siKras]
|
siRNA
|
yes |
|
|
yes |
yes |
|
EXP001878
|
iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to P…
|
2018 |
iRGD TPN (PEGylated vs non-PEG) biodistribution (healthy mice)
|
siRNA
|
yes |
|
|
yes |
no |
|
EXP001879
|
Fine Tuning of Core–Shell Structure of Hyaluronic Acid/Cell-Penetrating Peptide…
|
2018 |
Penetratin — NCs (Penetratin/siRNA core)
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP001880
|
Fine Tuning of Core–Shell Structure of Hyaluronic Acid/Cell-Penetrating Peptide…
|
2018 |
Penetratin — NPs-1 (HA 8 kDa shell)
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP001881
|
Fine Tuning of Core–Shell Structure of Hyaluronic Acid/Cell-Penetrating Peptide…
|
2018 |
Penetratin — NPs-2 (HA 200 kDa, low density shell)
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP001882
|
Fine Tuning of Core–Shell Structure of Hyaluronic Acid/Cell-Penetrating Peptide…
|
2018 |
Penetratin — NPs-3 (HA 200 kDa, high density shell)
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP001883
|
Fine Tuning of Core–Shell Structure of Hyaluronic Acid/Cell-Penetrating Peptide…
|
2018 |
Penetratin — NCs (Penetratin/siRNA core)
|
siRNA
|
yes |
|
|
yes |
yes |
|
EXP001884
|
Fine Tuning of Core–Shell Structure of Hyaluronic Acid/Cell-Penetrating Peptide…
|
2018 |
Penetratin — NPs-1 (HA 8 kDa shell)
|
siRNA
|
yes |
|
|
yes |
yes |
|
EXP001885
|
Fine Tuning of Core–Shell Structure of Hyaluronic Acid/Cell-Penetrating Peptide…
|
2018 |
Penetratin — NPs-2 (HA 200 kDa, low density shell)
|
siRNA
|
yes |
|
|
yes |
yes |
|
EXP001886
|
Fine Tuning of Core–Shell Structure of Hyaluronic Acid/Cell-Penetrating Peptide…
|
2018 |
Penetratin — NPs-3 (HA 200 kDa, high density shell)
|
siRNA
|
yes |
|
|
yes |
yes |
|
EXP001887
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 1 (Eledoisin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001888
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 2 (Cholecystokinin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001889
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 3 (Mastoparan)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001890
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 4 (Alpha synuclein-1)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001891
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 5 (Surfactant protein B)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001892
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 6 (Pleckstrin-1)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001893
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 7 (Amphipathic peptide 18a)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001894
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 8 (NCF-1)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001895
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 9 (Compstatin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001896
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 10 (Bnip3a)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001897
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 11 (Steryl sulfatase)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001898
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 12 (Orexin-a)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001899
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 13 (LDL-phospholipase A2)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001900
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 14 (Alamethicin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001901
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 15 (Acetylcholine receptor M2)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001902
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 16 (Model amphipathic peptide)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001903
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 17 (Aurein 1.2 analog b)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001904
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 18 (Silkworm paralytic peptide)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001905
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 19 (Peptaibol Chrysospermin C)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001906
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 20 (alpha Conotoxin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001907
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 21 (L-glutamate oxidase)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001908
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 22 (Distinctin antimicrobial peptide)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001909
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 23 (Eledoisin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001910
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 24 (Endothelin-1b)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001911
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 25 (Enterotoxin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001912
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 26 (Glucagon)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001913
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 27 (Antibiotic peptide)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001914
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 28 (Hepcidin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001915
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 29 (Antimicrobial peptide ISCT)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001916
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 30 (Kassinin-1)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001917
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 31 (Lactoferricin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001918
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 32 (Lactoferricin (short))
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001919
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 33 (Magainin 2)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001920
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 34 (Mastoparan-X)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001921
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 35 (Melittin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001922
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 36 (Microcin J25)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001923
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 37 (Motilin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001924
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 38 (Mria Conotoxin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001925
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 39 (Neurokinin-A)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001926
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 40 (Eledoisin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001927
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 41 (Antennapedia homeodomain (penetratin))
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001928
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 42 (Semliki mRNA capping enzyme NSP1)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001929
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 43 (Endothelin-1)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001930
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 44 (Endothelin-1 (short))
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001931
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 45 (Indolicidin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001932
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 46 (Hepatitis C envelope glycoprotein E1)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001933
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 47 (CD3-zeta)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001934
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 48 (Delta-toxin)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001935
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 49 (Non-structural protein 5A)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001936
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Peptide 50 (RAC-beta)
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001937
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Surfactant protein B peptide
|
siRNA
|
no |
|
|
yes |
yes |
|
EXP001938
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Orexin-a peptide
|
siRNA
|
no |
|
|
yes |
yes |
|
EXP001939
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Lactoferricin (25 aa)
|
siRNA
|
no |
|
|
yes |
yes |
|
EXP001940
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Lactoferricin (short, 13 aa)
|
siRNA
|
no |
|
|
yes |
yes |
|
EXP001941
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Surfactant protein B scrambled
|
siRNA
|
no |
|
|
yes |
no |
|
EXP001942
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Orexin scrambled
|
siRNA
|
no |
|
|
yes |
no |
|
EXP001943
|
Rational Design of a Biomimetic Cell Penetrating Peptide Library
|
2013 |
Lactoferricin scrambled
|
siRNA
|
no |
|
|
yes |
no |
|
EXP001945
|
Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-…
|
2021 |
GALA + CREKA (dual CPP) — GC-NP
|
siRNA
|
yes |
yes |
yes |
no |
no |
|
EXP001946
|
Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-…
|
2021 |
GALA (fusogenic CPP) — G-NP
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP001947
|
Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-…
|
2021 |
CREKA (tumor-homing peptide) — C-NP
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP001948
|
Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-…
|
2021 |
GALA + CREKA (dual CPP) — GC-NP/siEGFR
|
siRNA
|
yes |
yes |
yes |
no |
no |
|
EXP001949
|
Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-…
|
2021 |
GALA + CREKA (dual CPP) — GC-NP/siBRD4
|
siRNA
|
yes |
yes |
yes |
no |
no |
|
EXP001950
|
Serum Stability and Physicochemical Characterization of a Novel Amphipathic Pep…
|
2014 |
C6M1
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001951
|
A Dual-Ligand Liposomal System Composed of a Cell-Penetrating Peptide and a Mit…
|
2016 |
R8-modified MITO-Porter (no RNA aptamer)
|
RNA aptamer (2′-O-methyl, cholesterol-conjugated) [ligand; not therapeutic payload]
|
yes |
no |
|
no |
no |
|
EXP001952
|
A Dual-Ligand Liposomal System Composed of a Cell-Penetrating Peptide and a Mit…
|
2016 |
RP/R8-modified MITO-Porter (2.5 mol% Chol-RP)
|
RNA aptamer (2′-O-methyl, cholesterol-conjugated) [ligand; not therapeutic payload]
|
yes |
no |
|
no |
no |
|
EXP001953
|
A Dual-Ligand Liposomal System Composed of a Cell-Penetrating Peptide and a Mit…
|
2016 |
MRP/R8-modified MITO-Porter (2.5 mol% Chol-MRP)
|
RNA aptamer (2′-O-methyl, cholesterol-conjugated) [ligand; not therapeutic payload]
|
yes |
no |
|
no |
no |
|
EXP001954
|
A Dual-Ligand Liposomal System Composed of a Cell-Penetrating Peptide and a Mit…
|
2016 |
D-arm/R8-modified MITO-Porter (2.5 mol% Chol-D-arm)
|
RNA aptamer (2′-O-methyl, cholesterol-conjugated) [ligand; not therapeutic payload]
|
yes |
no |
|
no |
no |
|
EXP001955
|
Identification of a novel cell-penetrating peptide targeting human glioblastoma…
|
2015 |
Peptide1 (GBM-homing CPP)
|
|
yes |
no |
|
no |
no |
|
EXP001956
|
Identification of a novel cell-penetrating peptide targeting human glioblastoma…
|
2015 |
Peptide1-NSD (optimized GBM-homing CPP)
|
|
yes |
no |
|
no |
no |
|
EXP001957
|
Identification of a novel cell-penetrating peptide targeting human glioblastoma…
|
2015 |
Peptide1NSD–p16 MIS (CPP–cargo fusion)
|
|
yes |
no |
|
no |
no |
|
EXP001958
|
Identification of a novel cell-penetrating peptide targeting human glioblastoma…
|
2015 |
Peptide1NSD–p16 V95E (cargo control)
|
|
yes |
no |
|
no |
no |
|
EXP001959
|
Identification of a novel cell-penetrating peptide targeting human glioblastoma…
|
2015 |
R9 (nona-arginine) control CPP
|
|
yes |
no |
|
no |
no |
|
EXP001960
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
Chol-POD / siRNA polyplex
|
siRNA (siGLO; siLuc; NSC4)
|
yes |
no |
|
no |
no |
|
EXP001961
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
Palm-POD / siRNA polyplex
|
siRNA (siGLO; siLuc; NSC4)
|
yes |
no |
|
no |
no |
|
EXP001962
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
PLGA-PEG-POD / siRNA polyplex
|
siRNA (siGLO; siLuc; NSC4)
|
yes |
no |
|
no |
no |
|
EXP001963
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
POD / siRNA polyplex
|
siRNA (siGLO; siLuc; NSC4)
|
yes |
no |
|
no |
no |
|
EXP001964
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
Chol-POD + chloroquine / siRNA polyplex
|
siRNA (siLuc vs NSC4; siGLO)
|
yes |
yes |
yes |
no |
no |
|
EXP001965
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
Palm-POD + chloroquine / siRNA polyplex
|
siRNA (siLuc vs NSC4; siGLO)
|
yes |
yes |
yes |
no |
no |
|
EXP001966
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
PLGA-PEG-POD + chloroquine / siRNA polyplex
|
siRNA (siLuc vs NSC4; siGLO)
|
yes |
yes |
yes |
no |
no |
|
EXP001967
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
POD + chloroquine / siRNA polyplex
|
siRNA (siLuc vs NSC4; siGLO)
|
yes |
yes |
yes |
no |
no |