|
EXP001968
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
QN-Palm-POD / siRNA polyplex
|
siRNA (siLuc vs NSC4; siGLO)
|
yes |
yes |
yes |
no |
no |
|
EXP001969
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
Chol-POD / siGLO topical eye drop
|
Fluorescent siRNA (siGLO)
|
yes |
|
|
yes |
no |
|
EXP001970
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
Palm-POD / siGLO topical eye drop
|
Fluorescent siRNA (siGLO)
|
yes |
|
|
yes |
no |
|
EXP001971
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
QN-Palm-POD / siGLO topical eye drop
|
Fluorescent siRNA (siGLO)
|
yes |
|
|
yes |
no |
|
EXP001972
|
Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Cornea…
|
2019 |
QN-Palm-POD / siLuc topical eye drop (luciferase knockdown)
|
siRNA
|
no |
|
yes |
yes |
yes |
|
EXP001973
|
Self-Assembling Peptide-Based Nanoparticles for siRNA Delivery in Primary Cell …
|
2012 |
CADY
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001974
|
Self-Assembling Peptide-Based Nanoparticles for siRNA Delivery in Primary Cell …
|
2012 |
CADY
|
siRNA
|
no |
yes |
|
no |
no |
|
EXP001975
|
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzym…
|
2021 |
Ab-CPP-LSP-siRNA (cetuximab–PEG–LMWP–AANL–siRNA; ARC)
|
siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)
|
yes |
yes |
|
no |
no |
|
EXP001976
|
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzym…
|
2021 |
CPP-LSP-siRNA (PEG–LMWP–AANL–siRNA; no antibody)
|
siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)
|
yes |
yes |
|
no |
no |
|
EXP001977
|
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzym…
|
2021 |
CPP-LSP/siRNA physical mixture (LMWP-AANL + siRNA complex)
|
siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)
|
yes |
yes |
|
no |
no |
|
EXP001978
|
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzym…
|
2021 |
Ab-CPP-MSP-siRNA (cetuximab–PEG–LMWP–GGPLGVR–siRNA; ARC)
|
siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)
|
yes |
no |
|
no |
no |
|
EXP001979
|
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzym…
|
2021 |
Ab-CPP-siRNA (cetuximab–PEG–LMWP–siRNA; no substrate control)
|
siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)
|
yes |
no |
|
no |
no |
|
EXP001980
|
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzym…
|
2021 |
Ab-CPP-LSP-siRNA-Cy3 (ARC; cetuximab–PEG–LMWP–AANL–siRNA)
|
siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)
|
yes |
|
|
yes |
yes |
|
EXP001981
|
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzym…
|
2021 |
CPP-LSP-siRNA-Cy3 (PEG–LMWP–AANL–siRNA; no antibody)
|
siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)
|
yes |
|
|
yes |
yes |
|
EXP001982
|
Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzym…
|
2021 |
CPP-LSP-siRNA-Cy3/Ab physical mixture (noncovalent antibody addition)
|
siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)
|
yes |
|
|
yes |
yes |
|
EXP001983
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
Pip6a-PMO (Dmd exon23) single conjugate
|
|
no |
yes |
|
no |
no |
|
EXP001984
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
Pip6a-PMO (Acvr2b exon5) single conjugate
|
|
no |
yes |
|
no |
no |
|
EXP001985
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
Bi-specific D1 (one PMO on each Pip6a terminus)
|
|
no |
yes |
|
no |
no |
|
EXP001986
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
Bi-specific D2 (both PMOs attached at Pip6a C-terminus; Acvr2b PMO click)
|
|
no |
yes |
|
no |
no |
|
EXP001987
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
Bi-specific D3 (both PMOs attached at Pip6a C-terminus; Dmd PMO click)
|
|
no |
yes |
|
no |
no |
|
EXP001988
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
Bi-specific D4 (C-terminal disulfide linkage for second PMO)
|
|
no |
yes |
|
no |
no |
|
EXP001989
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
Bi-specific D2 (in vivo)
|
PMO (phosphorodiamidate morpholino oligomer; splice-switching oligonucleotide)
|
no |
|
|
yes |
yes |
|
EXP001990
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
Bi-specific D3 (in vivo)
|
PMO (phosphorodiamidate morpholino oligomer; splice-switching oligonucleotide)
|
no |
|
|
yes |
yes |
|
EXP001991
|
Bi-specific splice-switching PMO oligonucleotides conjugated via a single pepti…
|
2015 |
1:1 cocktail of single Pip6a-PMOs (Dmd + Acvr2b) (in vivo)
|
PMO (phosphorodiamidate morpholino oligomer; splice-switching oligonucleotide)
|
no |
|
|
yes |
yes |
|
EXP001992
|
Cell-Penetrating Peptide-Modified Graphene Oxide Nanoparticles Loaded with Rict…
|
2021 |
Octaarginine (R8)
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP001993
|
Cell-Penetrating Peptide-Modified Graphene Oxide Nanoparticles Loaded with Rict…
|
2021 |
Octaarginine (R8)
|
siRNA
|
no |
|
|
yes |
yes |
|
EXP001994
|
Functional peptide nanocarriers for delivery of novel anti-RelA RNA interferenc…
|
2015 |
OK-102 (stearoyl-oligopeptide)
|
nkRNA1 (long ssRNA that self-anneals)
|
no |
yes |
|
no |
no |
|
EXP001995
|
Functional peptide nanocarriers for delivery of novel anti-RelA RNA interferenc…
|
2015 |
OK-102 (stearoyl-oligopeptide)
|
nkRNA1 (long ssRNA that self-anneals)
|
no |
|
|
yes |
yes |
|
EXP001996
|
Functional peptide nanocarriers for delivery of novel anti-RelA RNA interferenc…
|
2015 |
OK-102 (stearoyl-oligopeptide)
|
PnkRNA1 (proline-derived modified nkRNA)
|
no |
yes |
|
no |
no |
|
EXP001997
|
Functional peptide nanocarriers for delivery of novel anti-RelA RNA interferenc…
|
2015 |
OK-102 (stearoyl-oligopeptide)
|
PnkRNA1 (proline-derived modified nkRNA)
|
no |
|
|
yes |
yes |
|
EXP001998
|
Targeted Activation of Cystic Fibrosis Transmembrane Conductance Regulator
|
2019 |
HIV-1 Tat CPP (recombinant Tat peptide)
|
Gapmer antisense oligonucleotide (ASO; 20-mer)
|
no |
yes |
|
no |
no |
|
EXP001999
|
Targeted Activation of Cystic Fibrosis Transmembrane Conductance Regulator
|
2019 |
HIV-1 Tat CPP (recombinant Tat peptide)
|
Gapmer antisense oligonucleotide (ASO; 20-mer)
|
no |
yes |
|
no |
no |
|
EXP002000
|
Targeted Activation of Cystic Fibrosis Transmembrane Conductance Regulator
|
2019 |
HIV-1 Tat CPP (recombinant Tat peptide)
|
Gapmer antisense oligonucleotide (ASO; 20-mer)
|
no |
yes |
|
no |
no |
|
EXP002001
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-DP7-ACP-T7 (DAT) (dual-functional peptide on liposome)
|
siRNA (duplex, 21-mer with 3′ TT overhangs)
|
yes |
yes |
yes |
no |
no |
|
EXP002002
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-DP7-ACP-T7 (DAT) (dual-functional peptide on liposome)
|
siRNA (duplex, 21-mer with 3′ TT overhangs)
|
no |
|
|
yes |
yes |
|
EXP002003
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-DP7-ACP-T7 (DAT) peptide
|
siRNA (Cy5-labeled for biodistribution imaging)
|
no |
|
|
yes |
no |
|
EXP002004
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-DP7-PEG2-T7 peptide
|
siRNA (Cy5-labeled for biodistribution imaging)
|
no |
|
|
yes |
no |
|
EXP002005
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-DP7-Gly6-T7 peptide
|
siRNA (Cy5-labeled for biodistribution imaging)
|
no |
|
|
yes |
no |
|
EXP002006
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-T7-ACP-DP7 peptide
|
siRNA (Cy5-labeled for biodistribution imaging)
|
no |
|
|
yes |
no |
|
EXP002007
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-T7-PEG2-DP7 peptide
|
siRNA (Cy5-labeled for biodistribution imaging)
|
no |
|
|
yes |
no |
|
EXP002008
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-T7-Gly6-DP7 peptide
|
siRNA (Cy5-labeled for biodistribution imaging)
|
no |
|
|
yes |
no |
|
EXP002009
|
A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery…
|
2024 |
Cholesterol-DP7-T7 peptide
|
siRNA (Cy5-labeled for biodistribution imaging)
|
no |
|
|
yes |
no |
|
EXP002010
|
siRNA delivery using amphipathic cell-penetrating peptides into human hepatoma …
|
2020 |
Peptide 1 (Ala)
|
siRNA
|
yes |
no |
|
no |
no |
|
EXP002011
|
siRNA delivery using amphipathic cell-penetrating peptides into human hepatoma …
|
2020 |
Peptide 2 (Aib)
|
siRNA
|
yes |
no |
|
no |
no |
|
EXP002012
|
siRNA delivery using amphipathic cell-penetrating peptides into human hepatoma …
|
2020 |
Peptide 3 (Deg)
|
siRNA
|
yes |
no |
|
no |
no |
|
EXP002013
|
siRNA delivery using amphipathic cell-penetrating peptides into human hepatoma …
|
2020 |
Peptide 4 (Hms)
|
siRNA
|
yes |
no |
|
no |
no |
|
EXP002014
|
siRNA delivery using amphipathic cell-penetrating peptides into human hepatoma …
|
2020 |
Peptide 5 (Ac5c)
|
siRNA
|
yes |
no |
|
no |
no |
|
EXP002015
|
siRNA delivery using amphipathic cell-penetrating peptides into human hepatoma …
|
2020 |
Peptide 6 (Dpg)
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP002016
|
A New Amphipathic, Amino-Acid-Pairing (AAP) Peptide as siRNA Delivery Carrier: …
|
2012 |
C6
|
siRNA
|
yes |
no |
|
no |
no |
|
EXP002017
|
Targeting glmS Ribozyme with Chimeric Antisense Oligonucleotides for Antibacter…
|
2021 |
pVEC
|
antisense oligonucleotide (ASO; chimeric)
|
no |
yes |
|
no |
no |
|
EXP002018
|
Targeting glmS Ribozyme with Chimeric Antisense Oligonucleotides for Antibacter…
|
2021 |
pVEC
|
antisense oligonucleotides (ASOs; chimeric)
|
no |
yes |
|
no |
no |
|
EXP002019
|
Cell Targeting Peptide Conjugation to siRNA Polyplexes for Effective Gene Silen…
|
2012 |
PCM + Tat
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP002020
|
Cell Targeting Peptide Conjugation to siRNA Polyplexes for Effective Gene Silen…
|
2012 |
PCM + Tat
|
siRNA
|
no |
|
|
yes |
no |
|
EXP002021
|
Treatment of Colon Cancer by Degradable rrPPC Nano-Conjugates Delivered STAT3 s…
|
2020 |
cRGD-R9
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP002022
|
Treatment of Colon Cancer by Degradable rrPPC Nano-Conjugates Delivered STAT3 s…
|
2020 |
cRGD-R9
|
siRNA
|
no |
|
|
yes |
yes |
|
EXP002023
|
Establishment of MicroRNA Delivery System by PP7 Bacteriophage-Like Particles C…
|
2017 |
TAT
|
pre-miRNA
|
yes |
yes |
|
no |
no |
|
EXP002024
|
Identification of a Novel Cell-Penetrating Peptide from Human Phosphatidate Pho…
|
2012 |
LPIN (LPIN3-derived CPP)
|
|
yes |
|
|
no |
no |
|
EXP002025
|
Identification of a Novel Cell-Penetrating Peptide from Human Phosphatidate Pho…
|
2012 |
LPIN (LPIN3-derived CPP)
|
|
no |
|
|
yes |
no |
|
EXP002026
|
Cell-Penetrating Peptides Derived from Viral Capsid Proteins
|
2011 |
CP12-22
|
|
yes |
|
|
no |
no |
|
EXP002027
|
Cell-Penetrating Peptides Derived from Viral Capsid Proteins
|
2011 |
CP9-22
|
viral RNA / dsRNA
|
yes |
|
|
no |
no |
|
EXP002028
|
Cell-Penetrating Peptides Derived from Viral Capsid Proteins
|
2011 |
CP9-22S
|
|
no |
|
|
no |
no |
|
EXP002029
|
Cell-Penetrating Peptides Derived from Viral Capsid Proteins
|
2011 |
CPNT
|
viral RNA / dsRNA
|
yes |
yes |
|
no |
no |
|
EXP002030
|
Cell-Penetrating Peptides Derived from Viral Capsid Proteins
|
2011 |
CP23-34
|
|
no |
|
|
no |
no |
|
EXP002031
|
Targeted OUM1/PTPRZ1 silencing and synergetic CDT/enhanced chemical therapy tow…
|
2022 |
RGD
|
siRNA (dual)
|
yes |
yes |
|
no |
no |
|
EXP002032
|
Targeted OUM1/PTPRZ1 silencing and synergetic CDT/enhanced chemical therapy tow…
|
2022 |
RGD
|
siRNA (dual)
|
no |
|
|
yes |
yes |
|
EXP002033
|
Improved method for synthesis of low molecular weight protamine–siRNA conjugate
|
2018 |
LMWP
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP002034
|
Highly penetrating nanobubble polymer enhances LINC00511-siRNA delivery for imp…
|
2021 |
TAT (CPP)
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP002035
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
Penetratin
|
siRNA
|
no |
|
|
no |
no |
|
EXP002036
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
HIV-TAT (47–57)
|
siRNA
|
no |
|
|
no |
no |
|
EXP002037
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
R10
|
siRNA
|
no |
|
|
no |
no |
|
EXP002038
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
CCMV Gag (7–25)
|
siRNA
|
no |
|
|
no |
no |
|
EXP002039
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
S413-PV
|
siRNA
|
no |
|
|
no |
no |
|
EXP002040
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
Transportan
|
siRNA
|
no |
|
|
no |
no |
|
EXP002041
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
pVEC
|
siRNA
|
no |
|
|
no |
no |
|
EXP002042
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
MPG
|
siRNA
|
no |
|
|
no |
no |
|
EXP002043
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
CADY
|
siRNA
|
no |
|
|
no |
no |
|
EXP002044
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
sC18
|
siRNA
|
no |
|
|
no |
no |
|
EXP002045
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
C6
|
siRNA
|
no |
|
|
no |
no |
|
EXP002046
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
K-FGF
|
siRNA
|
no |
|
|
no |
no |
|
EXP002047
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
Integrin β3 fragment
|
siRNA
|
no |
|
|
no |
no |
|
EXP002048
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
HBV translocation motif
|
siRNA
|
no |
|
|
no |
no |
|
EXP002049
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
Grb2 (SH2 domain)
|
siRNA
|
no |
|
|
no |
no |
|
EXP002050
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
HIV-1 gp41 (1–23)
|
siRNA
|
no |
|
|
no |
no |
|
EXP002051
|
Trends in the Binding of Cell Penetrating Peptides to siRNA: A Molecular Dockin…
|
2017 |
C105Y
|
siRNA
|
no |
|
|
no |
no |
|
EXP002052
|
TAT Peptides Mediated Small Interfering RNA Delivery to Huh-7 Cells and Efficie…
|
2009 |
HIV-1 TAT 47–57
|
siRNA
|
yes |
yes |
|
no |
no |
|
EXP002053
|
Tumor pH-functionalized and charge-tunable nanoparticles for the nucleus/cytopl…
|
2022 |
T-peptide (TAT–NGR)
|
miRNA
|
yes |
yes |
yes |
no |
no |
|
EXP002054
|
Tumor pH-functionalized and charge-tunable nanoparticles for the nucleus/cytopl…
|
2022 |
T-peptide (TAT–NGR)
|
miRNA
|
yes |
|
yes |
yes |
yes |
|
EXP002055
|
Tumor pH-functionalized and charge-tunable nanoparticles for the nucleus/cytopl…
|
2022 |
R-peptide (NLS)
|
|
yes |
|
yes |
no |
no |
|
EXP002056
|
Tumor pH-functionalized and charge-tunable nanoparticles for the nucleus/cytopl…
|
2022 |
R-peptide (NLS)
|
|
yes |
|
yes |
yes |
no |
|
EXP002057
|
Loading of cocktail siRNAs into extracellular vesicles via TAT-DRBD peptide for…
|
2022 |
3TD peptide (TAT–TAT–TAT–DRBD)
|
siRNA (cocktail)
|
yes |
yes |
|
no |
no |
|
EXP002058
|
siRNA suppression of hTERT using activatable cell-penetrating peptides in hepat…
|
2015 |
MMP2-activatable CPP (aCPP)
|
siRNA-encoding plasmid
|
yes |
yes |
|
no |
no |
|
EXP002059
|
A pH-Responsive Nanoplatform Based on Fluorescent Conjugated Polymer Dots for I…
|
2022 |
TAT peptide
|
siRNA
|
yes |
yes |
yes |
no |
no |
|
EXP002060
|
A pH-Responsive Nanoplatform Based on Fluorescent Conjugated Polymer Dots for I…
|
2022 |
TAT peptide
|
siRNA
|
yes |
|
yes |
yes |
yes |
|
EXP002061
|
A pH-Responsive Nanoplatform Based on Fluorescent Conjugated Polymer Dots for I…
|
2022 |
TAT-10H
|
siRNA
|
yes |
yes |
yes |
no |
no |
|
EXP002062
|
A pH-Responsive Nanoplatform Based on Fluorescent Conjugated Polymer Dots for I…
|
2022 |
TAT-10H
|
siRNA
|
yes |
|
yes |
yes |
yes |
|
EXP002063
|
Encapsulation of mRNA into Artificial Viral Capsids via Hybridization of a β-An…
|
2020 |
β-annulus
|
mRNA
|
yes |
no |
|
no |
no |
|
EXP002064
|
Encapsulation of mRNA into Artificial Viral Capsids via Hybridization of a β-An…
|
2020 |
Cys-β-annulus (dT20-SS)
|
mRNA
|
yes |
yes |
|
no |
no |
|
EXP002065
|
Efficient delivery of miR-122 to regulate cholesterol metabolism using a non-co…
|
2013 |
MPGΔNLS
|
miRNA
|
yes |
yes |
|
no |
no |
|
EXP002066
|
Efficient delivery of miR-122 to regulate cholesterol metabolism using a non-co…
|
2013 |
MPGΔNLS
|
miRNA
|
yes |
|
|
yes |
yes |
|
EXP002067
|
Enhanced CRISPR-Cas9 RNA system delivery using cell penetrating peptides-based …
|
2024 |
ADGN-AVA
|
CRISPR RNA (Cas9 mRNA + sgRNA)
|
yes |
yes |
|
no |
no |