Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations

Paper ID: PAPER000243
Year: 2025
DOI: 10.1038/s41551-024-01296-2
PMID: 39609561
Journal: Nature Biomedical Engineering
Source URL

Experiments

EXP001437 with TAT-ABE8e (covalent CPP fusion) (Guide RNA (sgRNA/epegRNA))
EXP001438 with CPP5-ABE8e (covalent CPP fusion) (Guide RNA (sgRNA/epegRNA))
EXP001439 with ANTP-ABE8e (covalent CPP fusion) (Guide RNA (sgRNA/epegRNA))
EXP001442 with CPP5-ABE8e (covalent CPP fusion) (Guide RNA (sgRNA/epegRNA))
EXP001443 with TAT-ABE8e (covalent CPP fusion) (Guide RNA (sgRNA/epegRNA))
EXP001444 with ANTP-ABE8e (covalent CPP fusion) (Guide RNA (sgRNA/epegRNA))