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1b (C24 lipidated sorbitol octaguanidine)

Peptide ID

PEPTIDE001314

Raw sequence

N/A (non-peptidic guanidine-based molecular transporter)

Clean backbone

Tokenized backbone

Sequence engineering

Stereochemistry

Modifications

Sorbitol scaffold bearing 8 guanidinium groups + C24 acyl chain (compound 1b, HCl salt). Used here as siRNA condenser (core formation) at N/P=3; MEND surface ligand STR-R8 (5 mol%).

Sequence length

56

Noncanonical residues

Experiments

• EXP001707 from Novel lipidated sorbitol-based molecular transporters for non-viral gene delive…