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RVG-9R
Peptide ID
PEPTIDE001376
Raw sequence
YTIWMPENPRPGTPCDIFTNSRGKRASNGGGGRRRRRRRRR
Clean backbone
YTIWMPENPRPGTPCDIFTNSRGKRASNGGGGRRRRRRRRR
Tokenized backbone
Y-T-I-W-M-P-E-N-P-R-P-G-T-P-C-D-I-F-T-N-S-R-G-K-R-A-S-N-G-G-G-G-R-R-R-R-R-R-R-R-R
Sequence engineering
Stereochemistry
Modifications
Chimeric rabies virus glycoprotein (RVG) fragment fused to 9 arginines (9R); used for electrostatic complexation with siRNA; SLN surface coated with low-MW chitosan (mucoadhesive, tight-junction modulation intent)
Sequence length
41
Noncanonical residues
Experiments
EXP001777
from
Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for A…