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GALA + CREKA (dual CPP) — GC-NP/siBRD4

Peptide ID
PEPTIDE001487
Raw sequence
GALA: nan; CREKA: CREKA
Clean backbone
WEAALAEALAEALAEHLAEALAEALEALAACREKA
Tokenized backbone
W-E-A-A-L-A-E-A-L-A-E-A-L-A-E-H-L-A-E-A-L-A-E-A-L-E-A-L-A-A-C-R-E-K-A
Sequence engineering
Stereochemistry
L-form
Modifications
CPP-modified redox-responsive polymer: GALA or CREKA conjugated to MAL-PEG-SS-PEI (PEG2k–SS–PEI25k). Disulfide bond enables GSH-triggered release. Peptide coupling: maleimide-terminated PEG-SS-PEI reacted with thiol-terminated peptide (1:1) then dialyzed/lyophilized.
Sequence length
35
Noncanonical residues

Experiments