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Lys-thyclotide (anti-miR-21)

Peptide ID

PEPTIDE001616

Raw sequence

NH2-Lys-A*A*C*A*T*C*A*G*T*C*T*G*A*T*A*A*G*C*T*A*-Lys-CONH2

Clean backbone

KAACATCAGTCTGATAAGCTAK

Tokenized backbone

K-A-A-C-A-T-C-A-G-T-C-T-G-A-T-A-A-G-C-T-A-K

Sequence engineering

C-terminal amidation

Stereochemistry

Modifications

Tetrahydrofuran backbone (thyclotide); terminal lysines; PNA analogue

Sequence length

22

Noncanonical residues

Experiments

• EXP002100 from Thyclotides, tetrahydrofuran-modified peptide nucleic acids that efficiently pe…