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RGD-targeted Au PENP / Bcl-2 siRNA polyplex

Peptide ID
PEPTIDE001875
Raw sequence
Arg-Gly-Asp (RGD)
Clean backbone
RGD
Tokenized backbone
R-G-D
Sequence engineering
PEGylated RGD targeting ligand (COOH-PEG-RGD) covalently linked to PEI; PEG spacer used; practical RGD number estimated ~4.6 per PEI vector by 1H NMR.
Stereochemistry
Modifications
RGD is PEGylated and conjugated to PEI surface; vector is PEI-(PEG-RGD)10-mPEG10 with entrapped Au nanoparticles.
Sequence length
3
Noncanonical residues

Experiments