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ASO

Linked experiment: EXP001636

Linked peptide: pAntp / Penetratin (Antennapedia 43–58)

Linked paper: Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo (1998)

RNA overview

RNA Type

ASO

Payload/target

cPNA r(18–38)-S–S-pAntp (antisense PNA to rat GalR1 nt 18–38)

Target gene/transcript

sense

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:CCATTCCCTTCACTGAGGTTC

Sense strand

CCATTCCCTTCACTGAGGTTC

Antisense strand

Chemical modifications

RNA modifications

21-mer PNA; biotinylated at PNA N-terminus for localization in some experiments; coupled to peptide via disulfide (S–S) through cysteine-extended PNA.