miRNA

Linked experiment: EXP002453

Linked peptide: RGD-decorated liposome / dipalmitoyl-GRGDSPA

Linked paper: Synergistic breast cancer therapy with RGD-decorated liposomes co-delivering mir-34a and cisplatin (2024)

RNA overview

RNA Type: miRNA
Payload/target: miR-34a
Target gene/transcript: tumor-suppressive miR-34a; apoptosis/drug-resistance pathway including Bcl-2/Bax and p53-associated signaling

Sequence information

Sequence reported in source article: yes
RNA sequence: UGGCAGUGUCUUAGCUGGUUGU
Sense strand: UGGCAGUGUCUUAGCUGGUUGU
Antisense strand

Chemical modifications

RNA modifications: No chemical modification stated; miR-34a complexed with protamine and encapsulated in liposome.