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siRNA

Linked experiment: EXP002505

Linked peptide: cRGD-PEG-PAsp(TEP)-Chol

Linked paper: Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer (2014)

RNA overview

RNA Type

siRNA

Payload/target

fluorescent siLuc model siRNA

Target gene/transcript

firefly luciferase reporter

Sequence information

Sequence reported in source article

yes

RNA sequence

sense: CUUACGCUGAGUACUUCGA-dTdT; antisense: UCGAAGUACUCAGCGUAAG-dTdT

Sense strand

CUUACGCUGAGUACUUCGA-dTdT

Antisense strand

UCGAAGUACUCAGCGUAAG-dTdT

Chemical modifications

RNA modifications

Alexa647-labeled siRNA used for tumor accumulation comparison