cyclo(RGDfK); main text reports cyclo-RGDfK/cRGD peptide, with N-terminal cysteine used for conjugation
Clean backbone
RGDFK
Tokenized backbone
R-G-D-F-K
Sequence engineering
cRGD peptide ligand installed at the distal end of PEG to target αvβ3 integrin; exact supplier construct likely includes an N-terminal cysteine for thiazolidine coupling.
Stereochemistry
cyclic RGDfK; D-Phe indicated by lowercase f in RGDfK
Modifications
Cyclic RGD peptide ligand covalently conjugated to PEG-PAsp(TEP) or PEG-PAsp(TEP)-Chol block copolymer