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PNA (antisense; fluorescein-labeled) + NLS peptide tail

Linked experiment: EXP001315

Linked peptide: TP10 (Transportan 10)

Linked paper: Application of Cell-Penetrating Peptides (CPP) to Enhance the Efficacy of Antisense Peptide Nucleic Acids (PNA) Molecules Delivery (2025)

RNA fields

RNA Type

PNA (antisense; fluorescein-labeled) + NLS peptide tail

RNA Payload Or Target

Fluo-PCSK9-PPT-EX1-Ahx-NLS (PCSK9-targeting PNA; sequence: Fluo-A-G-A-G-G-A-G-G-A-A-G-Ahx-Pro-Lys-Lys-Lys-Arg-Lys-Val-amide; MW 4477.62)

RNA Modifications

5/6-carboxyfluorescein (NHS-fluorescein); Ahx linker; C-terminal NLS peptide (PKKKRKV-amide).