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PNA (antisense oligonucleotide)

Linked experiment: EXP001428

Linked peptide: N/A (DNA tetrahedron vector; no peptide carrier)

Linked paper: Tetrahedral DNA Nanoparticle Vector for Intracellular Delivery of Targeted Peptide Nucleic Acid Antisense Agents to Restore Antibiotic Sensitivity in Cefotaxime-Resistant Escherichia coli (2017)

RNA fields

RNA Type

PNA (antisense oligonucleotide)

RNA Payload Or Target

blaCTX-M-group 1 (CTX-M β-lactamase) mRNA (field isolate harbors blaCTX-M-3 plasmid)

RNA Modifications

PNA4 13-mer base sequence (5'→3'): ttccttattctgg