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siRNA

Linked experiment: EXP001450

Linked peptide: CTX-R10 (chlorotoxin + deca-arginine)

Linked paper: Iron oxide nanoparticles decorated with functional peptides for a targeted siRNA delivery to glioma cells (2022)

RNA fields

RNA Type

siRNA

RNA Payload Or Target

MGMT siRNA (therapeutic target; chemoresistance sensitization) and siRFP reporter siRNA (validation in C6 cells)

RNA Modifications

Thiol-modified siRNA used for fluorescent labeling (BDP-maleimide, 1:1.2); Cy5-NHS labeling used for NP tracking (per Supplementary Methods).