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AMO (antisense morpholino oligonucleotide)

Linked experiment: EXP001689

Linked peptide: (RXRRBR)2XB

Linked paper: Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum (2011)

RNA fields

RNA Type

AMO (antisense morpholino oligonucleotide)

RNA Payload Or Target

ATM splicing mutation IVS28-159A>G (AT203LA cells; pseudoexon insertion; heterozygous)

RNA Modifications

Customized AMO sequence described previously (Du et al. 2007 PNAS, ref 10)