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ASO (antisense oligonucleotide; steric-blocking)

Linked experiment: EXP001728

Linked peptide: PepFect14 (PF14)

Linked paper: The nuclear concentration required for antisense oligonucleotide activity in myotonic dystrophy cells (2019)

RNA fields

RNA Type

ASO (antisense oligonucleotide; steric-blocking)

RNA Payload Or Target

CAG5 (triplet repeat-targeting ASO; sequence mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG)

RNA Modifications

Fully 2'-O-methyl (m) + phosphorothioate (*) 15-mer; Cy5 label at 5' used for imaging/quantitation in some experiments