siRNA

Linked experiment: EXP001752

Linked peptide: R8-PEI (octaarginine-modified PEI 25k)

Linked paper: Targeted melanoma therapy: High-efficiency siRNA delivery with R8-PEI dissolvable microneedles (2025)

RNA fields

RNA Type: siRNA
RNA Payload Or Target: BRAF siRNA (siRNA-4 selected; methoxylation-modified for stability) targeting BRAF in A375 melanoma
RNA Modifications: Methoxylation modification (to enhance stability); Cy3-labeled siRNA used for uptake/escape imaging