siRNA

Linked experiment: EXP001877

Linked peptide: iRGD TPN (PEGylated) therapeutic dosing [15:2.5:1 pTP-TAM-iRGD:pTP-PEG(5k)-iRGD:siKras]

Linked paper: iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer (2018)

RNA fields

RNA Type: siRNA
RNA Payload Or Target: KRAS (therapeutic anti-Kras siRNA in PDAC allograft model)
RNA Modifications: siKras.476 (targets murine+human KRAS) sense (no overhangs): ACCAUUAUAGAGAACAAAUUA