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siRNA

Linked experiment: EXP001945

Linked peptide: GALA + CREKA (dual CPP) — GC-NP

Linked paper: Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-responsive complex in triple negative breast cancer cells (2021)

RNA fields

RNA Type

siRNA

RNA Payload Or Target

EGFR + BRD4 co-silencing in TNBC (MDA-MB-231); anti-proliferation/invasion/migration

RNA Modifications

siEGFR1/2/3 and siBRD41/2/3 sequences were tested; core experiments used siEGFR + siBRD4 (1:1 mixture). Uptake studies used FAM-labeled negative control siRNA (FAM-siRNA).