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siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)

Linked experiment: EXP001975

Linked peptide: Ab-CPP-LSP-siRNA (cetuximab–PEG–LMWP–AANL–siRNA; ARC)

Linked paper: Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzyme cleavable linker mediated effective intracellular delivery of siRNA (2021)

RNA fields

RNA Type

siRNA (anti-EGFP; thiol-modified; Cy3/TAMRA labeled variants used for imaging)

RNA Payload Or Target

EGFP knockdown (anti-EGFP siRNA) in HCT116-EGFP cells

RNA Modifications

5′-GGCUACGUCCAGGAGCGCAdTdT-/3thiol/3 (antisense: 5′-UGCGCUCCUGGACGUAGCCdTdT-3′)