Cholesterol-DP7-ACP-T7 (DAT) (dual-functional peptide on liposome)

Peptide ID: PEPTIDE001532
Raw sequence: cholesterol-VQWRIRVAVIRK-ACP-HAIYPRH
Clean backbone: VQWRIRVAVIRKACPHAIYPRH
Tokenized backbone: V-Q-W-R-I-R-V-A-V-I-R-K-A-C-P-H-A-I-Y-P-R-H
Sequence engineering
Stereochemistry: L-form
Modifications: Cholesterol-conjugated DP7 (CPP/immune activator) linked by ACP (6-aminocaproic acid) to T7 (TfR-binding brain tumor targeting peptide); used to modify DOTAP:cholesterol (1:1) cationic liposome (DAT-LNP).
Sequence length: 22
Noncanonical residues

Experiments