ASO

Linked experiment: EXP002469

Linked peptide: eGLP-1-C / FOXO1 ASO 3b

Linked paper: Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell (2021)

RNA overview

RNA Type: ASO
Payload/target: IAPP ASO 43
Target gene/transcript: IAPP / islet amyloid polypeptide

Sequence information

Sequence reported in source article: yes
RNA sequence: TCAGTATTAAGTGCTGCAG
Sense strand
Antisense strand: TCAGTATTAAGTGCTGCAG

Chemical modifications

RNA modifications: cEt BNA/DNA gapmer; 5-methylcytidine; full phosphorothioate backbone; 5' TCA linker/spacer