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ASO

Linked experiment: EXP002471

Linked peptide: eGLP-1-C / FOXO1 ASO 3b

Linked paper: Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell (2021)

RNA overview

RNA Type
ASO
Payload/target
FOXO1 ASO 3b
Target gene/transcript
FOXO1 / forkhead box protein O1

Sequence information

Sequence reported in source article
yes
RNA sequence
TCATCTTCTTAAAATACCC
Sense strand
Antisense strand
TCATCTTCTTAAAATACCC

Chemical modifications

RNA modifications
cEt BNA/DNA gapmer; 5-methylcytidine; full phosphorothioate backbone; 5' d(TmCA) spacer; peptide-conjugated ASO