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siRNA

Linked experiment: EXP002506

Linked peptide: cRGD-PEG-PAsp(TEP)-Chol

Linked paper: Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer (2014)

RNA overview

RNA Type

siRNA

Payload/target

siPlk1

Target gene/transcript

PLK1 / polo-like kinase 1

Sequence information

Sequence reported in source article

yes

RNA sequence

sense: AGAuCACCCuCCUuAAAuAU; antisense: UAUUUAAgGAGGGUGAuCUUU

Sense strand

AGAuCACCCuCCUuAAAuAU

Antisense strand

UAUUUAAgGAGGGUGAuCUUU

Chemical modifications

RNA modifications

Selected bases 2′-O-methylated; lowercase letters in reported sequence indicate 2′-O-methylation