siRNA

Linked experiment: EXP001949

Linked peptide: GALA + CREKA (dual CPP) — GC-NP/siBRD4

Linked paper: Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-responsive complex in triple negative breast cancer cells (2021)

RNA fields

RNA Type: siRNA
RNA Payload Or Target: BRD4 silencing in TNBC (MDA-MB-231)
RNA Modifications: siEGFR1/2/3 and siBRD41/2/3 sequences were tested; core experiments used siEGFR + siBRD4 (1:1 mixture). Uptake studies used FAM-labeled negative control siRNA (FAM-siRNA).