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Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Corneal Epithelium Using a Modified Cell-Penetrating Peptide

Paper ID

PAPER000327

Year

2019

DOI

10.1016/j.omtn.2019.07.017

PMID

31476668

Journal

Molecular Therapy - Nucleic Acids

Source URL

Experiments

• EXP001960 with Chol-POD / siRNA polyplex (siRNA (siGLO; siLuc; NSC4))
• EXP001961 with Palm-POD / siRNA polyplex (siRNA (siGLO; siLuc; NSC4))
• EXP001962 with PLGA-PEG-POD / siRNA polyplex (siRNA (siGLO; siLuc; NSC4))
• EXP001963 with POD / siRNA polyplex (siRNA (siGLO; siLuc; NSC4))
• EXP001964 with Chol-POD + chloroquine / siRNA polyplex (siRNA (siLuc vs NSC4; siGLO))
• EXP001965 with Palm-POD + chloroquine / siRNA polyplex (siRNA (siLuc vs NSC4; siGLO))
• EXP001966 with PLGA-PEG-POD + chloroquine / siRNA polyplex (siRNA (siLuc vs NSC4; siGLO))
• EXP001967 with POD + chloroquine / siRNA polyplex (siRNA (siLuc vs NSC4; siGLO))
• EXP001968 with QN-Palm-POD / siRNA polyplex (siRNA (siLuc vs NSC4; siGLO))
• EXP001969 with Chol-POD / siGLO topical eye drop (Fluorescent siRNA (siGLO))
• EXP001970 with Palm-POD / siGLO topical eye drop (Fluorescent siRNA (siGLO))
• EXP001971 with QN-Palm-POD / siGLO topical eye drop (Fluorescent siRNA (siGLO))
• EXP001972 with QN-Palm-POD / siLuc topical eye drop (luciferase knockdown) (siRNA)